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KMID : 0381219740060120612
Journal of RIMSK
1974 Volume.6 No. 12 p.612 ~ p.621
Positive End-expiratory Pressure


Abstract
PEEP implies positive airway pressure at end expiration and throughout the expiratory phase of the respiratory cycle. Other terms that are used more or less interchangeably are CPPB, CPPV, CPAP and PEPP. PEEP primarily raises FRC and decreases shunting across the lung while changing the negative intrathoracic pressure to positive. This latter aspect may cause a decrease in venous return and a decrease in cardiac output. While Pa01 is usually improved, the net effect on oxygen transport is variable depending on a balance of factors. The effects on lung compliance are generally those of increasing lung compliance. There is little if any effect on diffusion loss secondary to interstitial fibrosis, PEEP seems particularly useful in acute respiratory distress syndromes (both adult and neonatal). It is contraindicated in the presence of hyperexpanded lungs (emphysema and asthma) and cardiogenic or hypovol emic shock. While an increased incidence of pneumothorax occurs with the use of PEEP, this may be due as much to the disease as the treatment.
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